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Hesperetin: A Flavonoid Compound



Hesperetin is a flavanone substance and broad-spectrum human UGT inhibitor. It is mainly derived from young fruits of the Rutaceae family, and is a product of hesperidin hydrolysis. It is also widely found in plant-derived substances such as fruits, flowers, and foods. It can induce apoptosis by activating p38 MAPK. In addition, hesperetin also has multiple biological and pharmacological activities such as antioxidant, anti-inflammatory, lipid-lowering, cardiovascular protection, and anti-tumor.

Hesperetin is used in health care drugs and health care products. It is also used as an additive in some cosmetics.


In Japan, hesperetin is used in food as an additive with the effect of vitamin P. In my country, hesperetin is mainly used as a drug raw material, and the main therapeutic effects of related drugs include stomachic, expectorant, antitussive, wind-repellent, diuretic, anti-reverse and stomach pain relief.


In the field of food, hesperetin has antioxidant, antibacterial, and anti-inflammatory effects. It is widely used in the preservation of fruits and vegetables, beverages, desserts, etc. It can not only extend the shelf life of food, but also improve the flavor of food and enhance consumers' taste experience; because it has many health benefits, such as antioxidant, anti-inflammatory, and anti-cancer, which added to some health foods, such as health products, nutritional supplements, etc., to meet people's needs for healthy life.


Hesperetin has a wide range of uses in the cosmetics field and can be used to make facial masks, skin care products, makeup and other products. Its antioxidant and anti-inflammatory effects can improve skin texture, delay aging, and reduce facial wrinkles. At the same time, hesperetin can also inhibit tyrosinase activity, playing a role in whitening and removing spots; it can promote blood circulation in the scalp, keep blood flowing in the scalp, repair damaged scalp barriers, effectively improve scalp resistance, stimulate scalp vitality, and thus improve hair quality.




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