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Curcumin

From Forbes HEALTH     Jul 20,2023

Research regarding the anti-aging properties of curcumin, an active compound found in turmeric, is promising, although more high-quality studies on human subjects are needed, says Woods. One 2020 research review in PharmaNutrition concluded that curcumin does have anti-inflammatory effects in the body, and a 2019 research review in the International Journal of Molecular Sciences concluded that curcumin appears to both reduce inflammation and suppress tumors.

Researchers continue to investigate whether curcumin might be protective against heart disease and whether curcumin supplementation could be used to help prevent and treat various brain diseases.

“The research isn’t super-conclusive, but I like what I see about curcumin,” says Woods. “It’s one of those things that has a very low bioavailability, so supplementing with it has a lower risk of toxicity, which is good.”

Since curcumin in food isn’t easily absorbed and metabolized by the body, a supplement can be a better option, says Woods. However, older adults should still eat fresh foods containing curcumin, too. Sprinkling a little turmeric in tea or coffee can be helpful.

The function of curcumin is primarily as an antioxidant and anti-inflammatory compound. Curcumin is a natural pigment found in the spice turmeric and is responsible for its yellow color. It has been extensively studied for its potential health benefits and is known to exhibit a wide range of biological activities.

Some of the key functions of curcumin include:

Anti-inflammatory activity: Curcumin has been shown to inhibit multiple pro-inflammatory pathways in the body, reducing inflammation and swelling. It can help alleviate symptoms of chronic inflammation and related diseases like arthritis.

Antioxidant activity: Curcumin has potent antioxidant properties, which means it can neutralize harmful free radicals in the body and protect cells from oxidative damage. This can help prevent chronic diseases and support overall health.

Enhanced brain function: Curcumin has been found to improve cognitive function and protect against neurodegenerative disorders like Alzheimer's disease. It may also promote the production of neurotrophic factors, which support brain health.

Anti-cancer properties: Curcumin has been studied for its potential anti-cancer effects. It can inhibit the growth of cancer cells, block the spread of tumors, and induce cancer cell death. However, more research is needed to fully understand its effectiveness in treating various types of cancer.

Improved cardiovascular health: Curcumin has shown promise in improving heart health by reducing inflammation, improving endothelial function, and lowering levels of LDL cholesterol. It may also help prevent blood clot formation and reduce the risk of heart disease.

Enhanced digestion: Curcumin stimulates the production of bile in the liver, promoting better digestion and nutrient absorption. It may also help alleviate symptoms of digestive disorders like irritable bowel syndrome (IBS) or ulcerative colitis.

It is important to note that curcumin's bioavailability is relatively low, meaning that it is not easily absorbed by the body. However, consuming it with black pepper or in combination with healthy fats like coconut oil can enhance its absorption. Additionally, curcumin supplements and specialized formulations with increased bioavailability are available.



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